KEVEYIS was shown to reduce the number, duration, and severity of attacks of Primary Periodic Paralysis.1
Results in Study 1: Hypokalemic patients treated with KEVEYIS had 2.2 fewer attacks per week than patients treated with placebo. Hyperkalemic patients treated with KEVEYIS had 3.9 fewer attacks per week than patients treated with placebo.2
Results in Study 2: Hyperkalemic patients treated with KEVEYIS had 2.3 fewer attacks per week than patients treated with placebo. For hypokalemic patients, the primary endpoint was the occurrence of an intolerable increase in attack frequency or severity, necessitating withdrawal from the treatment phase. Out of 15 patients, the majority reached acute worsening in the placebo phase.3
In study 1, the most common side effects of KEVEYIS were tingling or prickling sensations ("pins and needles"), feeling confused and having trouble paying attention, and changes in taste.1
KEVEYIS is a 50 mg tablet that is taken once or twice daily when starting therapy. Dosing can be increased or decreased at weekly intervals (or sooner in case of adverse reactions) based on individual response. The maximum recommended daily dose is 200 mg.1
If you are a patient or healthcare provider with questions about how to fill a prescription for KEVEYIS, or if you have any other questions related to KEVEYIS, call 844-KEVEYIS (538-3947).
What is KEVEYIS?
KEVEYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.
What should you tell your healthcare provider before taking KEVEYIS?
Tell your doctor if you are allergic to dichlorphenamide or other sulfa drugs; if you take high doses of aspirin, or if you have lung or liver disease; if you are pregnant, plan to become pregnant, or are breastfeeding or plan to breastfeed.
What should you know about KEVEYIS?
What are the most common side effects with KEVEYIS?
The most common side effects are a feeling of numbness, tingling or burning (“pins and needles”) in the toes, feet, hands or fingers; trouble with memory or thinking; feeling confused; and unpleasant taste in the mouth.
These are not all of the possible side effects of KEVEYIS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
© 2020 Strongbridge Biopharma plc
STRONGBRIDGE BIOPHARMA® is a registered trademark of the Strongbridge Biopharma plc. companies, which include Strongbridge Dublin Limited and Strongbridge U.S. Inc.
KEVEYIS® is a registered trademark licensed exclusively in the U.S. to Strongbridge Biopharma plc.
MLR-0010 V18 05/2020